Advancing Development of Synthetic Gene Regulators

Nominated by Kyoto University as an outstanding Ph.D. thesis  Reviews multitasking applications of next-generation sequencing (NGS) technologies for chemical biologists Describes low-cost Bind-n-Seq and small molecules based genomic pull-down development, identification of high-affinity binding sites for PIP conjugates using high-throughput sequencing, and the binding motif-guided redesign of PIPs